A hybrid model for evaluating dementia interventions Lead Investigator: Kim-Huong Nguyen Institution : University of Queensland E-Mail : kim.h.nguyen@uq.edu.au Proposal ID : 1052 Proposal Description: My research focuses on building economic models to evaluate dementia interventions, both pharmaceutical and non-pharmaceutical. In the last four years, I have built Markov simulation models based on data in the literature. However, the evaluations can only be as good as the model types and the data used to build the model. Therefore, I would like to build hybrid and flexible model using high quality data. Specific aims: 1. Use NACC data to develop a disease progression model based on age, gender, ethnicity, co-morbidity and changes in cognition, behavior and physical functioning. 2. Build an agent-based model drawing in formation from the disease progression model to predict dependency, care requirement and care setting. 3. Interact the agent-based model with a system dynamic model to examine resource utilization, both health and social care services and informal care provided by family members and how different dementia interventions can influence the level of resource use and total cost.